Anti-Human IgE (Ligelizumab)-Fc silent antibody (CAT#: CB-LX099-A) Datasheet

100 ug

Human

Human

Monoclonal

IgG1

Ligelizumab

Unconjugated

Recombinant

PBS, pH 7.4

The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.

This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.

Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.

IgE

IgE

Immunoglobulin E

Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has been found only in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum. IgE may have evolved as a last line of defense to protect against venoms.

IgE