Product Type
Fc Silent Antibody
Description
Anti-Human IFNR 1-Fc silent antibody is a Humanized monoclonal antibody targeting the A4B7. And it is intended for the research of Ulcerative colitis.
Research Area
Cell Biology, Immunology
Disease
Systemic lupus erythematosus
Size
100 ug
Species
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant
Buffer
PBS, pH 7.4
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Interferon alpha/beta receptor 1
Full Name
Interferon alpha/beta receptor 1
Background
IFNR associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
Alternative Names
Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1
Gene ID
3466
Uniprot ID
P17181
