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Anti-ICOS Fc Silent Antibody (CB-LX222-A)

Cat#: CB-LX222-A
Target: ICOS
Isotype: IgG4
Host: Humanized

Product Type Fc Silent Antibody

Description Anti-Human ICOS-Fc silent antibody is a Human monoclonal antibody targeting the EGFR & cMet. And it is intended for the research of Non-small cell lung cancer.

Research Area Cell Biology, Immunology

Antigen Distribution Biased expression in lymph node (RPKM 7.8), bone marrow (RPKM 6.5) and 9 other tissues

Disease Head and neck squamous cell carcinoma

Size 100 ug

Species Human

Clonality Monoclonal

Conjugation Unconjugated

Source Recombinant

Buffer PBS, pH 7.4

Application Notes The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.

Handling Advice This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.

Storage Instructions Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.

Official Name ICOS

Full Name Inducible T cell costimulator

Background The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]

Alternative Names ICOS; inducible T cell costimulator

Gene ID 29851

Uniprot ID Q9Y6W8

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All products and services are for Research Use Only. Do Not use in humans.

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Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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