Description
Anti-Human EGFR-Fc silent antibody is derived from clone VSTB 140, which is a Human monoclonal antibody targeting the EGFR. And it is intended for the research of Metastatic colorectal cancer, metastatic non-small cell lung cancer, head and neck cancer.
Research Area
Cell Biology, Immunology,
Antigen Distribution
Broad expression in placenta (RPKM 36.6), skin (RPKM 15.6) and 22 other tissues.
Disease
Metastatic colorectal cancer, metastatic non-small cell lung cancer, head and neck cancer
Immunogen
Recombinant Human EGFR protein
Application
Funcs, In vivo assay
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Epidermal growth factor receptor
Full Name
Epidermal growth factor receptor
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Alternative Names
Epidermal growth factor receptor; cell growth inhibiting protein 40; ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2
