Product Type
Fc Silent Antibody
Description
Anti-Human DR5-Fc silent antibody is derived from clone PRO95780, which is a Human monoclonal antibody targeting the DR5. And it is intended for the research of Chondrosarcoma, colorectal cancer, non-Hodgkin lymphoma, and non-small cell lung cancer..
Research Area
Cell Biology, Immunology
Antigen Distribution
DR5 is widely expressed in adult and fetal tissues, with notably high expression on tumor cells.
Disease
Chondrosarcoma, colorectal cancer, non-Hodgkin lymphoma, and non-small cell lung cancer.
Immunogen
Recombinant Human DR5 protein
Application
Agonist, ELISA, FuncS, FC, IF, IP, WB
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Tumor necrosis factor receptor superfamily member 10B
Full Name
Tumor necrosis factor receptor superfamily member 10B
Background
DR5 is expressed in a variety of solid tumors and hematologic malignancies, which are characteristically resistant to apoptosis.
Alternative Names
DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
