Description
Anti-Human CD64-Fc silent antibody is derived from clone H22, which is a Human monoclonal antibody targeting the CD64. And it is intended for the research of Autoimmune diseases, B cell malignancies.
Research Area
Cell Biology, Immunology,
Antigen Distribution
Biased expression in appendix (RPKM 19.0), placenta (RPKM 13.4) and 10 other tissues.
Disease
Autoimmune diseases, B cell malignancies
Immunogen
Recombinant Human CD64 protein
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Fc fragment of IgG receptor Ia
Full Name
Fc fragment of IgG receptor Ia
Background
CD64 (Cluster of Differentiation 64) is a type of integral membrane glycoprotein known as an Fc receptor that binds monomeric IgG-type antibodies with high affinity. It is more commonly known as Fc-gamma receptor 1 (FcγRI). After binding IgG, CD64 interacts with an accessory chain known as the common γ chain (γ chain), which possesses an ITAM motif that is necessary for triggering cellular activation.
Alternative Names
Fc fragment of IgG receptor Ia; High affinity immunoglobulin gamma Fc receptor I; CD64; CD64A; FCRI; IGFR1; FCGR1A
