Product Type
Fc Silent Antibody
Description
Anti-Human CD62-Fc silent antibody is a Humanized monoclonal antibody targeting the IL-23 p19. And it is intended for the research of Plaque psoriasis.
Research Area
Cell Biology, Immunology
Antigen Distribution
Broad expression in urinary bladder (RPKM 9.3), appendix (RPKM 7.3) and 20 other tissues.
Disease
Sickle cell disease
Size
100 ug
Species
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant
Buffer
PBS, pH 7.4
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Selectin P
Full Name
Selectin P
Background
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]
Alternative Names
Selectin P; Granule membrane protein 140kDa; antigen CD62
Gene ID
6403
Uniprot ID
Q6NUL9
