Product Type
Fc Silent Antibody
Description
Anti-Human CD49D-Fc silent antibody is a Human monoclonal antibody targeting the CD49D. And it is intended for the research of Multiple sclerosis (MS), Crohn's disease.
Research Area
Cell Biology, Immunology
Antigen Distribution
CD49D is a subunit of the integrin VLA-4, which is expressed on the cell surfaces of stem cells, progenitor cells, T and B cells, monocytes, natural killer cells, eosinophils, and neutrophils.
Disease
Multiple sclerosis (MS), Crohn's disease
Size
100 ug
Immunogen
Recombinant Human CD49D protein
Species
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant
Buffer
PBS, pH 7.4
Application
Block, FC
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Integrin alpha-4
Full Name
Integrin alpha-4
Background
The VCAM-1 and α4β1-integrin interaction is necessary for leukocyte adhesion, firm attachment, and transmigration across the blood-brain barrier into the CNS.
Alternative Names
CD49D; alpha 4 subunit of VLA-4 receptor; ITGA4; Integrin alpha-IV
Gene ID
3676
Uniprot ID
P13612
