Description
Anti-Human CD20 (REGN1979)-Fc silent antibody is derived from clone Utomilumab, which is a Human monoclonal antibody targeting the 4-1BB. And it is intended for the research of Diffuse large B-cell lymphoma.
Research Area
Cell Biology, Immunology,
Antigen Distribution
Biased expression in lymph node (RPKM 206.7), spleen (RPKM 109.2) and 2 other tissues.
Disease
Follicular lymphoma
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Full Name
Membrane spanning 4-domains A1
Background
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
Alternative Names
B1; S7; Bp35; CD20; FMC7; CVID5; MS4A2; LEU-16
