Description
Anti-Human CD194-Fc silent antibody is derived from clone KW-0761, which is a Human monoclonal antibody targeting the CD194. And it is intended for the research of Lymphoma.
Research Area
Cell Biology, Immunology,
Antigen Distribution
CCR4 is primarily expressed by Th2 and regulatory T cells in addition to expression on leukemic cells in cutaneous T-cell lymphoma (CTCL).
Immunogen
Recombinant Human CD194 protein
Application
Depletion, ELISA, FuncS, FC
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
C-C chemokine receptor type 4
Full Name
C-C chemokine receptor type 4
Background
CC chemokine receptor type 4 (CCR4) is a protein that belongs to the G protein-coupled receptor family and is a receptor for a variety of CC chemokines including MCP-1, MIP-1, RANTES, TARC, and Macrophage-derived chemokine. Chemokines are involved in the development, homeostasis, and function of the immune system and are known to regulate cell trafficking of various types of leukocytes.
Alternative Names
CD194; CKR-4; CCR-4; CCR4; K5-5
