Description
Anti-Human CD146-Fc silent antibody is derived from clone IR94, which is a Human monoclonal antibody targeting the CD146. And it is intended for the research of Autoimmune diseases.
Research Area
Cell Biology, Immunology,
Antigen Distribution
Broad expression in fat (RPKM 237.1), placenta (RPKM 102.0) and 17 other tissues.
Disease
Autoimmune diseases
Immunogen
Recombinant Human CD146 protein
Application
EL, WB, FC, Inhib
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
melanoma cell adhesion molecule
Full Name
melanoma cell adhesion molecule
Background
The CD146 protein (also termed melanoma cell adhesion molecule) is a medium-size transmembrane glycoprotein that belongs to the immunoglobulin superfamily. CD146 is expressed in some normal tissues and subsets of lymphocytes as well as in some other types of tumors, and its specificity is therefore low.
Alternative Names
Cell surface glycoprotein MUC18; MCAM; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD146; MUC18; HEMCAM; METCAM; MelCAM
