Description
Anti-Human CD11a-Fc silent antibody is derived from clone hu1124, which is a Human monoclonal antibody targeting the CD11a. And it is intended for the research of Neuroinflammation.
Research Area
Cell Biology, Immunology,
Antigen Distribution
CD11a is expressed on all leukocytes.
Immunogen
Recombinant Human CD11a protein
Application
Block, ELISA, FuncS, FC, IHC
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Integrin alpha-L
Full Name
Integrin alpha-L
Background
CD11a and CD18 are the Integrin alpha-L and beta-2 subunits that combine to form LFA-1, a glycoprotein and a member of the Integrin family. The Integrin alpha-L/beta-2 complex is a receptor for ICAM1, ICAM2, ICAM3, ICAM4 and F11R. LFA-1 participates in the immunological synapses between CD8+ T lymphocytes and antigen-presenting cells.
Alternative Names
ITGAL; integrin alpha L; LFA-1; LFA1A
