Product Type
Antibody
Description
Monoclonal antibody 568 reacts with epitopes on C5 and C5b. C5 participates in the activation of protein pathways in the complement system, which is an important factor in innate immunity. The complement pathway can be divided into activation pathway and lysis pathway. The activation pathway leads to the cleavage of the fifth complement component C5 into C5a and C5b through C3. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cell lysis.
Disease
Infectious diseases, Nephrology
Size
100 µg
Immunogen
Infectious diseases
Species
Human
Clonality
Monoclonal
Clone Number
568
Buffer
PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin.
Application
Immuno assays, Western blot
Application Notes
For Western blotting, the diluent that will be used depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution. The typical initial working dilution is 1:10.
Storage Instructions
Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least one year.
Alternative Names
C5; C5D; C5a; C5b; CPAMD4; ECLZB; complement component 5; complement C5
