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Anti-HGFA Antibody, Non-Fucosylated (Ab40) (CAT#: BioBet-978ZP) Datasheet

Target
HGFA
Isotype
IgG1
Description
Anti-HGFA Antibody, Non-Fucosylated (BioBet-978ZP) is a human monoclonal IgG1 antibody against HGFA. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced HGFA antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
HGFAC
Full Name
HGF activator
Background
This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants.
Alternative Names
HGFAC; HGF activator; HGFA; hepatocyte growth factor activator
Gene ID
3083
UniProt ID
Q9UK05
Cellular Localization
Extracellular region or secreted
Involvement in Disease
Diseases associated with HGFAC include Deafness, Autosomal Recessive 97.
Related Pathways
Its related pathways are Signaling by GPCR and Development HGF signaling pathway.
Function
Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
Post-translational modifications
1.Glycosylation at Asn48, Asn290, Asn468, and Asn546 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1
Antibody Clone
Ab40
Host
Human
Species Reactivity
Human
Description
The antibody binding to HGFA are used for the therapeutic and/or prophylactic treatment of a disease, such as cancer, tumor, cell proliferative disorder, an immune (such as autoimmune) disorder and angiogenesis-related disorder.
Antibody Indication
Cancer

Cancer

Related Products

Anti-HGFA Antibody, Non-Fucosylated (Ab39) (CAT#: BioBet-979ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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