Description
Anti-GPR87 Antibody, Non-Fucosylated (BioBet-951ZP) is a mouse monoclonal IgG antibody against GPR87. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced GPR87 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
GPR87
Full Name
G protein-coupled receptor 87
Background
This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589).
Alternative Names
GPR87; G protein-coupled receptor 87; GPR95; FKSG78; KPG_002; G-protein coupled receptor 87; orphan GPCR 87; G protein-coupled receptor 95; G-protein coupled receptor 95
Gene ID
53836
UniProt ID
Q9UK05
Cellular Localization
Plasma membrane
Involvement in Disease
Diseases associated with GPR87 include Squamous Cell Carcinoma and Lung Squamous Cell Carcinoma.
Related Pathways
Its related pathways are Peptide ligand-binding receptors.
Function
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.
Post-translational modifications
1.Glycosylation at Asn4, Asn25, and Asn33 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-951ZP
Description
The anti-GPR87 antibody are useful as drugs in the treatment of cancer.
Antibody Indication
Cancer
