Book a Meeting
Creative Biolabs - ADCC+ Antibody

Anti-GLP1R Antibody, Non-Fucosylated (BioBet-929ZP) (CAT#: BioBet-929ZP) Datasheet

Target
GLP1R
Isotype
IgG
Description
Anti-GLP1R Antibody, Non-Fucosylated (BioBet-929ZP) is a human monoclonal IgG antibody against GLP1R. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Diabetes
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced GLP1R antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
GLP1R
Full Name
Glucagon-like peptide 1
Alternative Names
GLP1R; glucagon-like peptide 1 receptor; GLP-1R; GLP-1-R; GLP-1 receptor
Gene ID
2740
UniProt ID
Q9UK05
Cellular Localization
Plasma membrane
Involvement in Disease
Diseases associated with GLP1R include Insulinoma and Hyperglycemia.
Related Pathways
Its related pathways are Integration of energy metabolism and Signaling by GPCR.
Function
Glucagon-like peptide 1 g protein-coupled receptor (GLP-1). Ligand binding triggers the activation of the signal cascade, leading to the activation of adenyl cyclase and the increase of intracellular cAMP levels. Regulates insulin secretion in the GLP-1 response (similar).
Post-translational modifications
N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-929ZP
Host
Human
Species Reactivity
Human
Description
The specific GLP-1R antibody identify and neutralize the activity of the GLP-1R would facilitate phamacodynamic studies. For example, the antibody could be used for a therapeutic to lower blood glucose and preserve the β-cells of the pancreas of diabetic patients.
Antibody Indication
Diabetes

Diabetes

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

  • *
  • *
USA

UK

Germany

ISO 9001 Certified - Creative Biolabs Quality Management System.