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Creative Biolabs - ADCC+ Antibody

Anti-Glial fibrillary acidic protein Antibody, Non-Fucosylated (BioBet-919ZP) (CAT#: BioBet-919ZP) Datasheet

Target
Glial fibrillary acidic protein
Isotype
IgG
Description
Anti-Glial fibrillary acidic protein Antibody, Non-Fucosylated (BioBet-919ZP) is a humanized monoclonal IgG antibody against Glial fibrillary acidic protein. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Nervous System Diseases
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Glial fibrillary acidic protein antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
GFAP
Full Name
growth differentiation factor 2
Background
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alternative Names
GFAP; glial fibrillary acidic protein
Gene ID
2670
UniProt ID
Q9UK05
Cellular Localization
Cytoplasm
Involvement in Disease
Diseases associated with GFAP include Alexander Disease and Central Neurocytoma.
Related Pathways
Its related pathways are Neuroscience and Signaling by GPCR.
Function
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Field of research
Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody; Astrocyte Marker antibody; Astrocyte Maturation Marker antibody; Neuroinflammation antibody; Brain Injury IHC Study antibody
Post-translational modifications
Phosphorylated by PKN1.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-919ZP
Host
Humanized
Species Reactivity
Human
Description
The humanized antibody directed against a glial fibrillary acidic protein (GFAP) are used for delivering therapeutic or diagnostic compounds across the mammal blood-brain barrier and cell membranes.
Antibody Indication
Nervous System Diseases

Nervous System Diseases

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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