Book a Meeting

Anti-Gastrokine 1 Antibody, Non-Fucosylated (CAT#: BioBet-925ZP) Datasheet

Target
Gastrokine 1
Isotype
IgG
Description
Anti-Gastrokine 1 Antibody, Non-Fucosylated (BioBet-925ZP) is a humanized monoclonal IgG antibody against Gastrokine 1. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Diabetes Type 2
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Gastrokine 1 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
GKN1
Full Name
gastric inhibitory polypeptide receptor
Background
The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.
Alternative Names
GKN1; gastrokine 1; FOV; CA11; AMP18; BRICD1; foveolin; gastrokine-1; AMP-18; BRICHOS domain containing 1; 18 kDa antrum mucosa protein
Gene ID
56287
UniProt ID
Q9UK05
Cellular Localization
Extracellular region or secreted
Involvement in Disease
Diseases associated with GKN1 include Gastric Cancer and Epithelial-Stromal Tgfbi Dystrophy.
Function
Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
Post-translational modifications
1.Modification sites at neXtProt 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-925ZP
Host
Humanized
Species Reactivity
Human
Description
The antibody binding protein specific for the GKN1 polypeptide are used for treatment of type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy.
Antibody Indication
Diabetes Type 2

Diabetes Type 2

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

  • *
  • *
  • *
USA

UK

Germany

ISO 9001 Certified - Creative Biolabs Quality Management System.