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Anti-FGFR2b Antibody, ADCC Enchanced (BioBet-CB-061LX) (CAT#: BioBet-CB-061LX) Datasheet

Target
FGFR2b
Isotype
IgG1
Description
Anti-FGFR2b Antibody, ADCC Enchanced (BioBet-CB-061LX) is a glycosylation-modified anti-FGFR2b therapeutic antibody.
Antibody Indication
Chronic lymphocytic leukemia; follicular lymphoma; some types of non-Hodgkin lymphoma (NHL);some non-cancer related illnesses
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced FGFR2b antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
FGFR2b
Full Name
Fibroblast growth factor receptor 2
Background
The tumor suppressor epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) induces human keratinocyte early differentiation. Moreover, protein kinases C (PKCs) are known to regulate the differentiation program in several cellular contexts, including keratinocytes.
Alternative Names
Fibroblast growth factor receptor 2; Fgfr; KGFR; Fgfr-; Fgfr7; Fgfr-2; Fgfr-7; Fgfr2b
Gene ID
14183
UniProt ID
E9Q5C2
Field of research
Cell Biology, Immunology,
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1
Antibody Clone
BioBet-CB-061LX
Host
Humanized
Species Reactivity
Human
Description
ADCC-Enhanced Anti-Human FGFR2b (Bemarituzumab) Antibody is derived from clone Bemarituzumab, which is a Humanized monoclonal antibody with enhanced ADCC activity. Antibody-dependent cellular cytotoxicity (ADCC) is an important function of antibody. It is a part of the humoral immune response to limit and contain infection. The antibody targets the FGFR2b, and it is intended for the research of Gastric/gastro-esophageal junction adenocarcinoma.
Antibody Indication
Gastric/gastro-esophageal junction adenocarcinoma

Gastric/gastro-esophageal junction adenocarcinoma

Related Products

Anti-FGFR2b Antibody, Non-Fucosylated (BioBet-1678ZP) (CAT#: BioBet-1678ZP)
Anti-FGFR2b Antibody, Non-Fucosylated (BioBet-1781ZP) (CAT#: BioBet-1781ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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