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Anti-E. coli Stx2A Antibody, Non-Fucosylated (BioBet-191ZP) (CAT#: BioBet-191ZP) Datasheet

Target
E. coli Stx2A
Isotype
IgG1, κ
Description
Anti-E. coli Stx2A Antibody, Non-Fucosylated (BioBet-191ZP) is a mouse monoclonal IgG1, κ antibody against E. coli Stx2A. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
STEC (Shiga-like toxin-producing Escherichia coli or E. coli serotype O121) infection causing diarrhea and HUS (hemolytic-uremic syndrome)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced E. coli Stx2A antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
E. coli Stx2A
Alternative Names
Setoxaximab; 1351470-17-1; Shiga toxin; E. coli Stx2; stx2; Stx2; Stx-2; Shiga-like toxin 2; SLT-2; SLT-II
Cellular Localization
Membrane
Involvement in Disease
Diseases associated with STX2 include Amelogenesis Imperfecta, Type Iiia and Acute Diarrhea.
Related Pathways
Its related pathways are Synaptic vesicle cycle and Sertoli-Sertoli Cell Junction Dynamics.
Function
Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Post-translational modifications
1.Modification sites at PhosphoSitePlus 2.Modification sites at neXtProt
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1, κ
Antibody Clone
BioBet-191ZP
Host
Mouse
Species Reactivity
E. coli
Description
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Mouse antibody to E. coli Stx2
Antibody Indication
STEC (Shiga-like toxin-producing Escherichia coli or E. coli serotype O121) infection causing diarrhea and HUS (hemolytic-uremic syndrome)

STEC (Shiga-like toxin-producing Escherichia coli or E. coli serotype O121) infection causing diarrhea and HUS (hemolytic-uremic syndrome)

Related Products

Anti-E. coli Stx2A Antibody, Highly Galactosylated (BioBet-GA-191ZP) (CAT#: BioBet-GA-191ZP)
Anti-E. coli Stx2A Antibody, Half-Life Extended (AES-0622-ZP1274) (CAT#: AES-0622-ZP1274)
Anti-E. coli Stx2A Antibody, FcγRIIB Binding Enhanced (AES-0622-ZP618) (CAT#: AES-0622-ZP618)
Anti-E. coli Stx2A Antibody, On-Target (AES-0622-ZP946) (CAT#: AES-0622-ZP946)
Anti-E. coli Stx2A Antibody, Recycling (AES-0622-ZP290) (CAT#: AES-0622-ZP290)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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