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Creative Biolabs - ADCC+ Antibody

Anti-CD56 Antibody, Non-Fucosylated (BioBet-391ZP) (CAT#: BioBet-391ZP) Datasheet

Target
CD56
Isotype
IgG
Description
Anti-CD56 Antibody, Non-Fucosylated (BioBet-391ZP) is a human monoclonal IgG antibody against CD56. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Small cell lung cancers (SCLC)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD56 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
NCAM1
Full Name
Neural Cell Adhesion Molecule 1
Background
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Alternative Names
Lorvotuzumab mertansine;1008106-64-6;IMGN901;huN901-DM1;BB-10901;IMGN901;NCAM1;neural cell adhesion molecule 1;CD56;NCAM;neural cell adhesion molecule, NCAM;antigen recognized by monoclonal 5.1H11;MSK39;
Gene ID
4684
UniProt ID
P13591
Cellular Localization
Extracellular region or secreted, Plasma membrane
Involvement in Disease
Diseases associated with NCAM1 include Rabiesand Bile Duct Cancer.
Related Pathways
Its related pathways are Neuroscience and RET signaling.
Function
The protein is a cell adhesion molecule, which participates in neuron-neuron adhesion, neurite outgrowth and neurite outgrowth.(Microbial infection) is the recipient of rabies virus.
Field of research
Developmental Biology antibody; Neuroscience antibody; General Lymphocyte Marker Study antibody; Natural killer cells antibody
Post-translational modifications
1.Glycosylation at Thr125, Asn222, Asn315, Asn347, Asn433, Asn459, and Asn488 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-391ZP
Host
Human
Species Reactivity
Human
Description
ADCC-enhanced Lorvotuzumab mertansine is a non-fucosylated anti-CD56 therapeutic biobetter antibody.
Antibody Indication
Small cell lung cancers (SCLC)

Small cell lung cancers (SCLC)

Related Products

Anti-CD56 Antibody, Half-Life Extended (AES-0622-ZP1151) (CAT#: AES-0622-ZP1151)
Anti-CD56 Antibody, Recycling (AES-0622-ZP167) (CAT#: AES-0622-ZP167)
Anti-CD56 Antibody, FcγRIIB Binding Enhanced (AES-0622-ZP495) (CAT#: AES-0622-ZP495)
Anti-CD56 Antibody, On-Target (AES-0622-ZP823) (CAT#: AES-0622-ZP823)
Anti-CD56 Antibody, Highly Galactosylated (BioBet-GA-391ZP) (CAT#: BioBet-GA-391ZP)

All products and services are for Research Use Only. Do Not use in humans.

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