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Anti-CD37 Antibody, Non-Fucosylated (BioBet-129ZP) (CAT#: BioBet-129ZP) Datasheet

Target
CD37
Isotype
VH - V-kappa - CH2 - CH3
Description
ADCC-enhanced Otlertuzumab is a non-fucosylated anti-CD37 therapeutic biobetter antibody.
Antibody Indication
Non-Hodgkin's lymphoma (NHL)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD37 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CD37
Full Name
CD37 Molecule
Background
CD37 (CD37 Molecule) is a Protein Coding gene.

Among its related pathways are Hematopoietic cell lineage.

An important paralog of this gene is CD82.
Alternative Names
CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37;
Gene ID
951
UniProt ID
P11049
Cellular Localization
Membrane
Involvement in Disease
Diseases associated with CD37 include Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Osteogenesis Imperfecta, Type Iii.
Related Pathways
Its related pathways are Hematopoietic cell lineage.
Field of research
Immune System antibody
Post-translational modifications
1.Glycosylation at Asn170, Asn183, and Asn188 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
VH - V-kappa - CH2 - CH3
Antibody Clone
Otlertuzumab
Host
Humanized
Species Reactivity
Human
Description
Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD37. Otlertuzumab is a humanized monoclonal antibody designed for the treatment of cancer
Antibody Indication
Non-Hodgkin's lymphoma (NHL)

Non-Hodgkin's lymphoma (NHL)

Related Products

Anti-CD37 Antibody, FcγRIIB Binding Enhanced (AES-0622-ZP492) (CAT#: AES-0622-ZP492)
Anti-CD37 Antibody, Recycling (AES-0622-ZP164) (CAT#: AES-0622-ZP164)
Anti-CD37 Antibody, Non-Fucosylated (BioBet-128ZP) (CAT#: BioBet-128ZP)
Anti-CD37 Antibody, On-Target (AES-0622-ZP820) (CAT#: AES-0622-ZP820)
Anti-CD37 Antibody, Highly Galactosylated (BioBet-GA-128ZP) (CAT#: BioBet-GA-128ZP)
Anti-CD37 Antibody, Half-Life Extended (AES-0622-ZP1148) (CAT#: AES-0622-ZP1148)
Anti-CD37 Antibody, Highly Galactosylated (BioBet-GA-129ZP) (CAT#: BioBet-GA-129ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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