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Creative Biolabs - ADCC+ Antibody

Anti-CD25 Antibody, Highly Galactosylated (BioBet-GA-303ZP) (CAT#: BioBet-GA-303ZP) Datasheet

Target
CD25
Isotype
IgG
Description
Anti-CD25 Antibody, Highly Galactosylated (BioBet-GA-303ZP) is a human IgG antibody against CD25 which contains with a high level of galactosylation.
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD25 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
IL2RA
Full Name
Interleukin 2 Receptor Subunit Alpha
Background
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Alternative Names
IL2RA; interleukin 2 receptor; alpha; p55; CD25; IL2R; TCGFR; IDDM10; interleukin-2 receptor subunit alpha; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; HuMax-TAC
Gene ID
3559
UniProt ID
P01589
Cellular Localization
Membrane
Genecards
6008
Involvement in Disease
Its related pathways are RET signaling and Signaling by GPCR.
Related Pathways
Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
Function
Immune System antibody; Pre-B Cell Marker antibody
Field of research
1.Glycosylation at Asn70, Asn89, Thr218, Thr224, Thr229, and Thr237 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-GA-303ZP
Host
Human
Species Reactivity
Human
Description
Anti-CD25 antibody is a Human antibody of IgG class that binds to an CD25.

Related Products

Anti-CD25 Antibody, On-Target (AES-0622-ZP688) (CAT#: AES-0622-ZP688)
Anti-CD25 Antibody, Highly Galactosylated (BioBet-GA-304ZP) (CAT#: BioBet-GA-304ZP)
Anti-CD25 Antibody, Highly Galactosylated (BioBet-GA-305ZP) (CAT#: BioBet-GA-305ZP)
Anti-CD25 Antibody, Half-Life Extended (AES-0622-ZP1016) (CAT#: AES-0622-ZP1016)
Anti-CD25 Antibody, Non-Fucosylated (BioBet-303ZP) (CAT#: BioBet-303ZP)
Anti-CD25 Antibody, FcγRIIB Binding Enhanced (AES-0622-ZP360) (CAT#: AES-0622-ZP360)
Anti-CD25 Antibody, Non-Fucosylated (BioBet-304ZP) (CAT#: BioBet-304ZP)
Anti-CD25 Antibody, Non-Fucosylated (BioBet-305ZP) (CAT#: BioBet-305ZP)

All products and services are for Research Use Only. Do Not use in humans.

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