Description
Anti-CD23 Antibody, Highly Galactosylated (BioBet-GA-115ZP) is a chimeric IgG1, κ antibody against CD23 which contains with a high level of galactosylation.
Antibody Indication
Allergic asthma
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD23 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CD23
Alternative Names
Lumiliximab; 357613-86-6; IDEC-152; P5E8; gomiliximab; FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A), FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2;
Gene ID
2208
UniProt ID
P06734
Cellular Localization
Plasma membrane, Extracellular region or secreted Cytosol
Genecards
3612
Involvement in Disease
Its related pathways are Signaling by GPCR and Hematopoietic cell lineage.
Related Pathways
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Field of research
1.N- and O-glycosylated. 2.The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1, κ
Antibody Clone
BioBet-GA-115ZP
Description
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant chimeric (primate/human) antibody expressed in CHO. Lumiliximab is a monoclonal antibody that targets CD23. It acts as an immunomodulator. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
Antibody Indication
Allergic asthma
