Description
Anti-CD15 Antibody, Non-Fucosylated (BioBet-099ZP) is a mouse monoclonal IgG antibody against CD15. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD15 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CD15
Alternative Names
fanolesomab;NeutroSpec;225239-31-6;RB5;CD15;3-fucosyl-N-acetyl-lactosamine
Cellular Localization
Golgi apparatus
Involvement in Disease
Diseases associated with FUT4 include Hodgkin's Lymphoma, Mixed Cellularity and Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance.
Related Pathways
Its related pathways are Glycosphingolipid biosynthesis - lacto and neolacto series and Metabolism.
Function
May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Post-translational modifications
1.Glycosylation at Asn216 and Asn315 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-099ZP
Description
Recombinant Mouse antibody to Human CD15. Technetium (99mTc) fanolesomab (trade name NeutroSpec) is a mouse monoclonal antibody formerly used to aid in the diagnosis of appendicitis. It is labeled with a radioisotope, technetium-99m (99mTc).
