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Anti-CCL17 Antibody, Non-Fucosylated (BioBet-626ZP) (CAT#: BioBet-626ZP) Datasheet

Target
CCL17
Isotype
IgG
Description
Anti-CCL17 Antibody, Non-Fucosylated (BioBet-626ZP) is a human monoclonal IgG antibody against CCL17. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Inflammatory Diseases
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CCL17 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CCL17
Full Name
chemokine (C-C motif) ligand 17
Background
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Alternative Names
CCL17; chemokine (C-C motif) ligand 17; TARC; ABCD-2; SCYA17; A-152E5.3; C-C motif chemokine 17; CC chemokine TARC; T cell-directed CC chemokine; small-inducible cytokine A17; thymus and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 17
Gene ID
6361
Cellular Localization
Extracellular region or secreted
Involvement in Disease
Diseases associated with CCL17 include Eosinophilic Pneumonia and Paragonimiasis.
Related Pathways
Its related pathways are PEDF Induced Signaling and Akt Signaling.
Function
Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
Post-translational modifications
1.Modification sites at neXtProt 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-626ZP
Host
Human
Species Reactivity
Human
Description
The anti-CAPRIN-1 antibody may be any type of monoclonal antibody as long as it can exhibit anti-tumor activity.
Antibody Indication
Inflammatory Diseases

Inflammatory Diseases

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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