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Anti-CCL11 Antibody, Highly Galactosylated (BioBet-GA-095ZP) (CAT#: BioBet-GA-095ZP) Datasheet

Target
CCL11
Isotype
IgG4, κ
Description
Anti-CCL11 Antibody, Highly Galactosylated (BioBet-GA-095ZP) is a human IgG4, κ antibody against CCL11 which contains with a high level of galactosylation.
Antibody Indication
Allergies, severe ocular
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CCL11 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CCL11
Full Name
C-C Motif Chemokine Ligand 11
Background
CCL11 (C-C Motif Chemokine Ligand 11) is a Protein Coding gene.
Diseases associated with CCL11 include Asthma and Human Immunodeficiency Virus Type 1.
Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system.
Gene Ontology (GO) annotations related to this gene include chemokine activity.
An important paralog of this gene is CCL2.
Alternative Names
Bertilimumab; cat-213; 375348-49-5; CAT-213; CAT213; iCo-008; CAT-212; CCL11; chemokine (C-C motif) ligand 11; SCYA11, small inducible cytokine subfamily A (Cys Cys), member 11 (eotaxin); eotaxin; eotaxin 1; MGC22554; eotaxin-1; C-C motif chemokine 11;
Gene ID
6356
UniProt ID
P51671
Cellular Localization
Extracellular region or secreted
Genecards
10610
Involvement in Disease
Its related pathways are PEDF Induced Signaling and Akt Signaling.
Related Pathways
Among its related pathways are PEDF Induced Signaling and Akt Signaling.
Field of research
O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG4, κ
Antibody Clone
BioBet-GA-095ZP
Host
Human
Species Reactivity
Human
Description
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to human CCL11. Bertilimumab is a human monoclonal antibody that binds to eotaxin-1, an important regulator of overall eosinophil function. It was to be used to treat severe allergic disorders.
Antibody Indication
Allergies, severe ocular

Allergies, severe ocular

Related Products

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Anti-CCL11 Antibody, Non-Fucosylated (BioBet-095ZP) (CAT#: BioBet-095ZP)
Anti-CCL11 Antibody, Recycling (AES-0622-ZP42) (CAT#: AES-0622-ZP42)
Anti-CCL11 Antibody, FcγRIIB Binding Enhanced (AES-0622-ZP370) (CAT#: AES-0622-ZP370)

All products and services are for Research Use Only. Do Not use in humans.

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Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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