Description
Anti-C35 Antibody, Non-Fucosylated (BioBet-1227ZP) is a mouse monoclonal IgG antibody against C35. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced C35 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
MIEN1
Full Name
migration and invasion enhancer 1
Alternative Names
MIEN1; migration and invasion enhancer 1; C35; ORB3; XTP4; RDX12; C17orf3
Gene ID
84299
Cellular Localization
Plasma membrane, Cytosol
Involvement in Disease
Diseases associated with MIEN1 include Breast Large Cell Neuroendocrine Carcinoma and Prostate Cancer.
Function
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
Post-translational modifications
1.Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation 2.Modification sites at PhosphoSitePlus 3.Modification sites at neXtProt
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
1F2
Description
The anti-C35 antibody are used for treatment for C35-positive cancers comprising testing for the expression of receptor molecules such as HER2, EGFR, and IGFR.
Antibody Indication
Cancer
