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Creative Biolabs - ADCC+ Antibody

Anti-AGS-8 Antibody, Non-Fucosylated (AGS-8M4) (CAT#: BioBet-546ZP) Datasheet

Target
AGS-8
Isotype
IgG1k
Description
Anti-AGS-8 Antibody, Non-Fucosylated (BioBet-546ZP) is a human monoclonal IgG1k antibody against AGS-8. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Ovarian Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced AGS-8 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
AGS-8
Full Name
AGS-8
Background
AGS-8 is a novel cell surface protein expressed on tumor cells in patients with ovarian cancer.
Alternative Names
AGS-8
Cellular Localization
Extracellular region or secreted
Involvement in Disease
Diseases associated with FNDC1 include Prostate Leiomyosarcoma and Prostate Sarcoma.
Function
May be an activator of G protein signaling.
Post-translational modifications
1.Glycosylation at Asn149, Ser713, Ser717, Thr732, Ser737, Ser738, Ser741, Ser759, Ser761, Thr762, Ser846, Ser847, Ser851, Thr852, Ser855, and Asn1661 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1k
Antibody Clone
AGS-8M4
Host
Human
Species Reactivity
Human
Description
AGS-8M4 (ASP6183) is an IgG1k fully human monoclonal antibody (MAb) directed to AGS-8, used for treatment of ovarian cancer. AGS-8M4 was well tolerated at all dose levels.
Antibody Indication
Ovarian Cancer

Ovarian Cancer

All products and services are for Research Use Only. Do Not use in humans.

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