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Non-fucosylated Anti-Human IgE (Omalizumab) Therapeutic Antibody (CAT#: BioBet-030ZP) Datasheet

Target
IgE
Isotype
IgG1
Description
ADCC-enhanced Omalizumab is a non-fucosylated anti-IgE therapeutic biobetter antibody.
Indication
Asthma
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced IgE antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
IgE
Full Name
Immunoglobulin E
Alternative Names
IgE
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1
Antibody Clone
Omalizumab
Host
Mouse
Species Reactivity
Human
Description
Omalizumab was originally designed to reduce sensitivity to allergens. Omalizumab is a recombinant DNA-derived humanized IgG1k monoclonal antibody that specifically binds to free human immunoglobulin E (IgE.
Indication
Chronic Idiopathic Urticaria
Moderate Asthma
Severe Asthma

Omalizumab inhibits the binding of IgE to the high-affinity IgE receptor (FcεRI) on the surface of mast cells and basophils. Omalizumab binds to free IgE with higher affinity than IgE itself, which binds to the high-affinity FcγRI receptor on basophils. This binding property allows omazumab to neutralize typical IgE-mediated responses without causing degranulation of basophils or cross-linking of IgE with basophils.

Chronic Idiopathic Urticaria
Moderate Asthma
Severe Asthma

Related Products

Highly Galactosylated Anti-IgE (Omalizumab) Antibody (CAT#: BioBet-GA-030ZP)
Non-Fucosylated Anti-Human IgE (47H4v5) Therapeutic Antibody (CAT#: BioBet-1727ZP)
BetterBet™ Anti-IgE Half-Life Extended Antibody (CAT#: AES-0622-ZP1216)
BetterBet™ Anti-IgE On-Target Antibody (CAT#: AES-0622-ZP888)
BetterBet™ Anti-IgE Recycling Antibody (CAT#: AES-0622-ZP232)
BetterBet™ Anti-IgE FcγRIIB Binding Enhanced Antibody (CAT#: AES-0622-ZP560)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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