Non-Fucosylated Anti-Human B7-H6 (BioBet-1595ZP) Therapeutic Antibody - Creative Biolabs
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Non-Fucosylated Anti-Human B7-H6 (BioBet-1595ZP) Therapeutic Antibody (CAT#: BioBet-1595ZP) Datasheet

Target
B7-H6
Isotype
IgG
Description
ADCC-Enhanced anti-B7-H6 is a non-fucosylated therapeutic biobetter antibody engineered by Creative Biolabs' Afuco™ technology platform.
Indication
Tumor
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced B7-H6 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
NCR3LG1
Full Name
natural killer cell cytotoxicity receptor 3 ligand 1
Background
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).
Alternative Names
NCR3LG1; natural killer cell cytotoxicity receptor 3 ligand 1; B7H6; B7-H6; DKFZp686O24166
Gene ID
Cellular Localization
Plasma membrane
Related Pathways
Its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation.
Function
Triggers NCR3-dependent natural killer cell activation.
Post-translational modifications
1.Glycosylation at Asn43, Asn57, Asn174, Asn208, Asn216, Asn242, and Asn260 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-1595ZP
Host
Human
Species Reactivity
Human
Description
This is antibody, antigen receptors, and bispecific T-cell engagers having specificity for B7-H6, and can be used for diagnosis and treatment of disorders associated with B7-H6 expression.
Indication
Tumor

Tumor

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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