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Non-fucosylated Anti-Human Tumour Associated Glycoprotein 72 (anatumomab mafenatox) Therapeutic Antibody (CAT#: BioBet-451ZP) Datasheet

Target
tumour associated glycoprotein 72
Isotype
IgG
Description
ADCC-enhanced anatumomab mafenatox is a non-fucosylated anti-tumour associated glycoprotein 72 therapeutic biobetter antibody.
Indication
Renal cell carcinoma (RCC)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced tumour associated glycoprotein 72 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TAG72
Alternative Names
anatumomab mafenatox;676258-98-3;ABR-214936;TAG-72;Tumor-associated glycoprotein 72;CA 72.4;TAG 72;Tumor associated Glycoprotein 72;CA 72-4
Cellular Localization
Nucleus
Involvement in Disease
Diseases associated with RNMT include Bowen-Conradi Syndrome and Microphthalmia, Isolated 6.
Related Pathways
Its related pathways are HIV Transcription Elongation and Gene Expression.
Function
The catalytic subunit of mrna-cap methyltransferase RNMT:RAMAC complex, which methylates the N7 position of the added guanosine to the 5'cap structure of mRNAs. Binding RNA containing 5'end GpppC.
Post-translational modifications
1.Ubiquitination at Lys163 and Lys208 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
anatumomab mafenatox
Host
Mouse
Species Reactivity
Human
Description
ADCC-enhanced anatumomab mafenatox is a non-fucosylated anti-tumour associated glycoprotein 72 therapeutic biobetter antibody.
Indication
Renal cell carcinoma (RCC)

Renal cell carcinoma (RCC)

Related Products

Highly Galactosylated Anti-tumour associated glycoprotein 72 (anatumomab mafenatox) Antibody (CAT#: BioBet-GA-451ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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