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Fc Engineered Anti-Human CGRP Therapeutic Antibody, a CDC-Enhanced Biobetter [Lot: CB20-PZ94] (CAT#: Biobet-C094ZP) Datasheet

Target
CGRP
Isotype
Human IgG4, κ
Description
CDC-Enhanced Galcanezumab is a Fc-modified anti-CGRP therapeutic biobetter antibody. Creative Biolabs' advanced CDC-enhanced antibody platform allows for the production of Fc engineered therapeutic CDC⁺ antibodies. By mutating key amino acids of the Fc region of Galcanezumab, Galcanezumab exhibits a greater binding capacity to C1q, thereby achieving enhanced CDC activity.
Indication
Migraine
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced rituximab. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CALCA and CALCB
Alternative Names
CALCA; calcitonin related polypeptide alpha; CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I
Gene ID
UniProt ID
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
Human IgG4, κ
Description
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CGRP. Galcanezumab is a humanized monoclonal antibody that can be potentially used in the treatment of Osteoarthritis (OA). It binds to and inhibits the activity of CGRP.
Indication
Migraine

Migraine

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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