Description
Anti-PRG-3 Antibody, Non-Fucosylated (BioBet-1547ZP) is a mouse monoclonal IgG antibody against PRG-3. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced PRG-3 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Alternative Names
PRG3; proteoglycan 3; MBP2; MBPH; prepro-MBPH; prepro-major basic protein homolog; eosinophil major basic protein homolog;
Cellular Localization
Cytoplasmic granule
Related Pathways
Its related pathways are Innate Immune System.
Function
Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.
Post-translational modifications
1.Modification sites at neXtProt 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Clone
BioBet-1547ZP
Description
The antibody is capable of binding to the PRG-3 protein, and uses as a pharmaceutical composition, cell growth inhibitor, and an anticancer agent. Examples of the type of cancer include hepatocellular carcinoma, lung cancer, colon cancer, and glioblastoma.
Antibody Indication
Cancer
