Human NF-kB-Luc Reporter T Lymphocytes have the Lucia luciferase gene (a secreted luciferase reporter gene), driven by the IFN-β minimal promoter, which is fused with a total of 5 copies of NF-κB transcription Response element and 3 copies of c-Rel binding site.

Human NF-kB-Luc Reporter T Lymphocytes also express a secreted embryonic alkaline phosphatase (SEAP) reporter gene, which works together with five IFN-stimulated response elements under the control of the ISG54 minimal promoter.

As a result, JHuman NF-kB-Luc Reporter T Lymphocytes can simultaneously study the NF-κB pathway by monitoring the activity of Lucia luciferase and the IRF pathway (by evaluating the activity of SEAP).

•Stable expression of Fc receptor CD16A on cell surface
•Stable expression of Luc luciferase reporter gene under the control of ISG54 minimal promoter fused with six NFAT response elements

ADCC reporter effector cells